The BIOSTAT® RM, a fully GMP compliant, single-use, wave-mixed bioreactor and single use Flexsafe bags are proven for a broad range of different cell lines incl. CHO, NS0, SF9, E.coli and mesenchymal stem cells.
Volumes:
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100 ml to 100 L
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Two Rocker sizes : BIOSTAT® RM 20/50 and BIOSTAT® RM 200
Why choose BIOSTAT® RM?
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Excellent Cell Growth and Robustness
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Security of Supply & Consistent Quality
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Easy to Use Rocker with Advanced Control Capabilities
Cells
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Mammalian, insect and plant cell
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Suspension or adherent cells on micro-carriers
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Shear sensitive cells such as stem cells
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Low to medium density microbial cultures
Process Step
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Seed expansion for large bioreactors
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GMP Production
Purpose
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Process transfer from shake or T-flask
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Rapid material supply for pre-clinical trials
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Production of recombinant proteins, mAbs and vaccines
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Continuous cultures with reported cell densities of 150 million cells/ml
BIOSTAT® RM 20/50 basic
stand-alone unit for benchtop use
It is a perfectly sized, stand-alone bioreactor for benchtop use. An exchangeable bag holder fits bags from 1 L to 50 L total volume.
Basic rocker with integrated local controller, Air | CO2 mixing module and load cells is the optimal choice for straight forward applications such as seed generation.
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Space-saving, individual control of two bags on the same platform
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Advanced alarming and safety features for safe cultivation
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Reduced manual handling by automated sampling function
Advanced Control System
BIOSTAT® B Control Tower with BIOSTAT® RM 20/50 and Flexsafe RM bag
Do you want to run fully automated and controlled batch, fed-batch or high cell density perfusion cultures?
Combine your BIOSTAT® RM basic rocker with our BIOSTAT® B control tower and use Flexsafe RM bags equipped with single-use pH and DO probes.
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Advanced control of gas mixture and volume, filling volume and substrate addition
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Extra small space requirement with TWIN configuration – two culture systems controlled by one controller at the same time
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The BIOSTAT® B controller is designed to work with a conventional glass vessel, the single-use UniVessel® SU and the BIOSTAT® RM rocker
BIOSTAT® RM 200
The BIOSTAT® RM 200 is your choice for larger scale seed expansion and production of material for preclinical and clinical studies.
It supports working volumes from 10 L up to 100 L.
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Low consumable costs compared to stirred single-use bioreactors
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Designed for automated batch and fed-batch processes
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Reliable single-use probes for measurement of pH and DO